The school is administered by a Board of Governors and an administrative staff that consists of the Headmaster, Assistant Headmasters, and Senior Housemasters. The Board of Governors oversees the general administration of the school and defines the scope of the school’s efforts to offer the best education and character training. The members of the board, all Santaclausians, were: E.R. Hayford-Chairman (Bishop’s Representative), James Mercer (Bishop’s Representative), S.H. Annancy (Bishop’s Representative), C.K. Annan (Government Representative), Nana Awudu Amanfo II (J.C. Amoah-Old Boys Representative), and Dr. H. Mercer Ricketts (PTA Representative). The Board was reconstituted on June 7th, 1980.
In 1988, another board was appointed under the chairmanship of William Tandoh. An eminent industrialist at Tema, Mr. Tandoh resigned after a year and passed on the chairmanship to Mr. Charles Stanley-Pierre (Chairman), Other Board Members were: Bishop Robert Okai (Archbishop of the Province of West Africa) Ken Ampratwum, Sampson Hammond(PTA Representative), John Asmah, Ato Ampiah, J.D. Anaman, Solomon Arthur (Teachers Representative), J.K. Nketsia (Non-Teaching Staff Representative), J.D. Sam.
The current Board of Governors are as follows:
- Rt. Rev. Alex K. Asmah- Chairman
- Mrs. Vivian Adu Poku – Director general representative
- Hon. Nana Kweku Awuku – Metro assembly representative
- Mr. Alfred Osmomd Hughes – P.T.A representative
- Mr. Samuel Kofi Agudogo – Headmaster
- Mrs. Dorcas B. Asare – Metro Director of Education
- Mrs. Martha Agyeman – Regional Director
- Mr. Emmanuel Baah – Teaching staff representative
- Mr. Phillip Yebesi – Old Boys representative
- Rev Ing. William Hutton-Mensah Anglican Church representative
- Mrs. Regina Appiah-Sekyere – Manager Anglican Schools
- Ms. Leviticus Mensah – Non teaching staff
- Rev. C.O.P David Ampah Bennin – Police comm (security interest)
- Rev. Prof. Harold Amonoo-Kofi – Old boys representative
- Rev. Faustina Baidoo (Assist headmistress admin) – Secretary
- Hon. Hussienu Shaibu – Metro Assembly representative